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Zeemine (Rivastigmine)
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Zeemine

Zeemine is a cholinesterase inhibitor used for the treatment of mild to moderate Alzheimer's disease and Parkinson's. The drug can be administered orally or via a transdermal patch; the latter form reduces the prevalence of side effects, which typically include nausea and vomiting.

Other names for this medication:
Rivadem, Rivamer, Rivasmine, Rivastigmine, Srivasmine, Zeemine

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Also known as: Rivastigmine

Description

Zeemine (rivastigmine) improves the function of nerve cells in the brain. It works by preventing the breakdown of a chemical that is important for the processes of memory, thinking, and reasoning. People with dementia usually have lower levels of this chemical.

Zeemine is used to treat mild to moderate dementia caused by Alzheimer's or Parkinson's disease.

Zeemine is not a cure for Alzheimer's or Parkinson's disease.

The use of Zeemine in in patients under 18 years of age is not recommended.

Dosage

This medicine comes with patient instructions. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions.

To use the skin patch:

Apply the patch right away after removing it from the protective pouch. Do not cut it into smaller pieces and do not touch the sticky surface of the patch. Apply the patch to a clean, dry, and hairless skin area on your upper or lower back, upper arm, or chest. Do not put the patch over rashes, cuts, or irritated skin. Avoid putting the patch on areas where it could be rubbed off by tight clothing. Do not use the patch if the pouch seal is broken or the patch is cut, damaged, or changed in any way. Press the patch firmly in place for 30 seconds with the palm of your hand to make sure that the edges of the patch stick well. The patch should stay in place, even when you are showering, bathing, or swimming. Apply a new patch if it falls off. After 24 hours, remove the patch. Choose a different place on your skin to apply the new patch. Do not put a new patch in the same place for at least 14 days. Do not leave the patch on for more than 24 hours. It will not work as well after that time and it may irritate your skin. After removing a used patch, fold the patch in half with the sticky sides together. Place the folded, used patch in its protective pouch. Make sure to dispose of it out of the reach of children and pets. Try to change the patch at the same time each day. If you forget to change the patch at the usual time, remove the patch you are wearing and put on a new patch. After that, apply a fresh patch at the usual time on the next day. Do not put cream, lotion, ointment, oil, or powder on the skin area where the patch will be placed. Do not touch your eyes after you touch the patch. Do not expose the patch to direct sources of heat, such as heating pads, electric blankets, heat lamps, saunas, hot tubs, heated water beds, or direct sunlight for long periods of time. Make sure you wash your hands with soap and water before and after applying the patch.

Do not stop using this medicine without asking your doctor. If you have not used your medicine for several days in a row, do not start using it again without talking to your doctor first. You may need to start the medicine again using a lower dose.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For transdermal dosage form (patch): For dementia associated with Alzheimer's disease or Parkinson's disease: Adults—At first, one 4.6 milligram (mg) patch once a day. After at least 4 weeks, your doctor will increase your dose as needed. If you have mild to moderate Alzheimer's disease or Parkinson's disease dementia, usual dose is 9.5 mg patch or 13.3 mg patch per day. If you have severe Alzheimer's disease, 13.3 mg patch per day. However, the dose is usually not more than one 13.3 mg patch per day. Children—Use and dose must be determined by your doctor.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include severe nausea, vomiting, salivation, sweating, slow heartbeats, weak or shallow breathing, fainting, or seizure (convulsions).

Storage

Store the patches at room temperature in a closed container, away from heat, moisture, and direct light.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Zeemine dosage information

Side effects

The most common side effects associated with Zeemine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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In the present study, nine healthy men performed two 45-min bouts of one-legged knee extension exercise: one bout with restricted blood flow, and the other with nonrestricted blood flow to the working cleocin t gel price muscle. Serum neuron specific enolase levels correlate with patient prognosis for advanced lung cancer. The diet moderately poor in protein should be given at creatinine values in the serum 4 mg/100ml and the diet strongly poor in protein from 8 mg/100 ml (prophylactically perhaps from 6 mg/100 ml). Lysis of antibody-coated human red cells by peripheral blood monomuclear cells: altered effector cell profile after treatment of target cells with enzymes. Melancholia and barbiturates: a controlled EEG, body and eye movement study of sleep. The model consisted of cycles of 3 months and a time horizon of 4 years.

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Proceedings of the scientific conference of the European Academy of Paediatric Dentistry. Findings of 12 single case studies which documented and analyzed the course of features typical in an acute psychotic episode during a milieu-therapeutic treatment are reported (criteria: DSM-III-schizophrenia). (b) The aim of this study is to evaluate the efficacy of closure of anterior palatal fistula using myomucosal superior lip flap. The purpose of this study was to determine the changes in the plasma concentration of rocuronium and the reversal of its neuromuscular blockade after the intravenous infusion of Org 25969, the novel neuromuscular block-reversal agent, in anesthetized guinea pigs. The origin of cortical surround receptive fields studied in the barrel cortex. Active epididymitis and chronic interstitial orchitis were present in two patients, with some spread of the inflammation into the fibrotic peritesticular tissues. Mice with moderate, severe, or very severe hyperglycemia underwent transplantation with a marginal number of islets (350 into BALB/c mice and 700 into NOD mice). Infertile women who accepted the COH and IVF-ET were included prospectively. Parameters were lipitor reviews uk quantified at barbell liftoff (LO), when the barbell passed the knees (KP), and at lift completion.

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