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Nifedipress (Nifedipine)

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Nifedipress is a dihydropyridine calcium channel blocker. Nifedipress is used to: treat high blood pressure (hypertension), prevent chronic stable angina (chest pain). Nifedipress was the first calcium channel blocker to be shown to significantly reduce the development of new overt heart failure in patients with coronary artery disease. Excellent blood-pressure control in recent clinical trials has been shown to result in significant protection against stroke. Nifedipress works by opening up blood vessels in the body to lower blood pressure and improve the supply of blood and oxygen to the heart. Calcium channel blockers do not change the amount of calcium in your blood or bones.

Other names for this medication:
Adalate, Buconif, Calchan, Cardalin, Cardicon, Cardiosol, Cardules, Conetrin, Coracten, Cordilat, Duranifin, Emaberin, Epilat, Farmalat, Fenidina, Glopir, Hypan, Nifangin, Nifecard, Nifecor, Nifedigel, Nifedipin, Nifedipino, Nifedipress, Nipress, Nirena, Nycopin, Pabalat, Tensomax

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Nifedipress XL. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Nifedipress and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Nifedipress are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Nifedipress if you are allergic to Nifedipress components. Do not take Nifedipress if you're pregnant or you plan to have a baby, or you are a nursing mother. Nifedipress can harm your baby. Do not use Nifedipress in combination with salt substitutes or potassium supplements. If you want to achieve most effective results without any side effects it is better to avoid alcohol. Avoid grapefruit juice during treatment with Nifedipress. Try to be careful using Nifedipress if you suffer from kidney disease, liver disease, diseases of the heart or blood vessels (sick sinus syndrome), aortic stenosis, heart failure, low blood pressure, or coronary artery disease. Do not stop taking Nifedipress suddenly.

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By reverse transcriptase-polymerase chain reaction, mRNA for the ER is clearly identified in primary human granulosa cells obtained at the time of oocyte retrieval. Urea, a small organic compound, has lower rejection than ionic compounds such as ammonium, nitrate, and nitrite, indicating the critical role of electrostatic interaction in rejection. We therefore decided to test the hypothesis that GPs and occupational health physicians issue more short-term certificates and use partial sick-listing more often than other physicians. Chest X-ray after tracheostomy is not necessary unless clinically indicated. In addition, beclomethasone inhaler decreases the incidence and severity of postoperative sputum. Near-infrared sub-bandgap all-silicon photodetectors: state of the art and perspectives.

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Relationship between lice infestation and leather damage in cattle. Furthermore, it has potential to aid in certification of new thoracic surgeons. However, very little is known about the actions of sevoflurane and desflurane on recombinant GABAA receptors. However, there was no significant difference in the electrophoretic mobility and the fluorescent emission spectrum between these variants at any pH. Response of the cultivated tomato and its wild salt-tolerant relative Lycopersicon pennellii to salt-dependent oxidative stress: The root antioxidative system. We believe that our patient suffered from raised intracranial pressure directly as a result amaryl 1mg tablet of decreasing intracranial volume secondary to CED. Statin Selection in Qatar Based on Multi-indication Pharmacotherapeutic Multi-criteria Scoring Model, and Clinician Preference.

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Erythropoietin concentrations in the vitreous body from patients with proliferative diabetic retinopathy. The effect of SP on Isc could be blocked significantly by pretreatment with four substances. They attached Bacillus subtilis spore film dosimeters (VioSpor) on the back between their shoulders. UPGMA analysis recovered clusters of band patterns that were compared to the distribution of species within the genus Azospirillum. The development of vaccines effective for infants and vaccines inducing protection against serogroup B would be expected to have a substantial impact on disease. The remaining 114 patients were diagnosed as having NTG, and their right eye data were used for analysis. Cutting the dorsalis pedis artery proximal to the flap can elevate this flap with reverse vascular flow. Physiological effects of the dyes on the circadian rhythm of activity in the eye are described. Renal Genetics Interest Group - 3rd Annual Renal Genetics Symposium.

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Unlike the poorly controlled patients, UBM parameters in group 1 were comparable to those in the controls. Preservation of the porcine pancreas with HTK and Euro-Collins solution: studies in a reperfusion system. The value of transcutaneous nerve stimulation (TNS) for palliative relief of pain is reviewed. The nucleotide sequencing process produces not only the sequence of nucleotides, but also associated quality values. At present, conservation measures do not adequately protect all of the biological features that render the islands so important in terms of conservation at a regional and global level. Impaired consciousness during seizures may be mediated by ictal propagation to the thalamus. Angiolipomas, a rare manifestation of HIV-associated lipodystrophy. This treatment resulted in normalization of the characteristics of renal blood flow. Anatomo-clinical aspects of so-called idiopathic pernicious myocarditis. Excess non-synonymous substitutions suggest that positive selection episodes occurred during the evolution of DNA-binding domains in the Arabidopsis R2R3-MYB gene family.

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Whether DNR can activate to impair the sensitivity of cancer cells remains unknown. We investigated the long-term outcome of patients with thyroid orbitopathy treated with orbital radiotherapy using quantitative clinical measurements and orbital computed tomographic morphometric changes. Recognition of ligands by toll-like receptor (TLR) 2 requires interactions with other TLRs. Surgical ciliated cyst: a delayed complication in a case of maxillary orthognathic surgery. The results suggest that radionuclide esophageal emptying test using a solid meal remains a useful objective study of esophageal function and may have an important future role in the follow-up evaluation of treatment for achalasia. By comparison, the importance of greenhouse gases in driving glacier retreat during the most recent deglaciation, the last major interval of global warming, is unclear due to uncertainties in the timing of retreat around the world. Changes in cardiovascular activity during an increase in biliary tract pressure in rabbits. Changes in day-care organizations, better living conditions, and restriction of antibiotic use seems to be useful precautions to prevent the emerging and colonization with penicillin-susceptible or -resistant S.

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After surgical or traumatical cyclodialysis dangerous hypotony can occur. Histology revealed focal and diffuse damage to the targeted kidneys and vascular rupture in both kidneys with complete necrosis of the walls of intralobular arteries and veins. These studies included needle EMG, motor conduction velocities of deep peroneal and median nerves, sensory conduction velocities, sensory potentials, and nerve potentials of the sural and medium nerves. This enzyme converts arachidonic acid (AA) into several metabolites, some of which have been identified as modulators of mitogenesis and apoptosis. This report summarizes the available evidence and describes the key questions that will need to be addressed with the goal of standardizing the care of patients with cardiac surgery-associated acute kidney injury (CSA-AKI) and improving outcomes. Simulations show that the bandwidth of this branched intracellular nanotube FET (BIT-FET) is high enough for it to record fast action potentials even when the nanotube diameter is decreased to 3 nm, a length scale well below that accessible with other methods. The industrial processes to manufacture commonly consumed condiments amaryl tabs 4mg and seasonings, such as soy sauce, bouillon cubes, fish sauce, spices, and other relevant products, are described. However, some Canadian chiropractors respond that most claims that chiropractic can cure disease originate in the US, and that Canadian chiropractors are conservative in their claims.

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On the basis of the results obtained, the authors believe that surgical treatment appears to most indicated in patients belonging to the lower risk classes (Child A and B), whereas endoscopic sclerotherapy is better suited to patients belonging to the higher risk class (Child C). Workplace health promotion and labour market performance of employees. The most well-known PFCs are perfluorooctane sulfonic acid (PFOS), perfluorooctanoic acid (PFOA) and their derivatives belonging to the group of perfluoroalkylated substances. In this review, the authors revisit the methods, technical constraints and the different action spectra of PSII photoinactivation reported to date and compare them against the diverse mechanisms proposed. Age-dependent change in myocardial cardiac glycoside receptor (Na,K-pump) concentration in children. Febrile nonhemolytic transfusion reaction (FNHTR) has been identified as a pivotal reason for prestorage universal WBC reduction. The overall survival rate for patients with a high level of AMF-R gene expression with tumors was significantly worse than for those individuals whose tumors had low AMF-R expression. This finding may be due to the smaller hand and the relative quantities of different tissues. The ability of Fla-typing schemes to discriminate between strains of Campylobacter jejuni. Large surveys auditing feeding regimen in the ICU consistently reported hypocaloric 23 enteral feedings patterns and many studies described the association between 24 energy deficit and increased complication rate.

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Case report: thrombosis of the inferior vena cava--an unusual presentation of protein C deficiency. Of the 329 students who completed the questionnaire, twenty-two (7 percent) were current smokers, and fifteen (5 percent) were ex-smokers. They are less than that found in previous studies of prehospital RSI and are similar to those reported in studies of in-hospital emergency RSI undertaken in the emergency department or ward setting. The effect of microaerosolized hydrogen peroxide on bacterial and viral poultry pathogens. In vitro studies included morphological observations, karyotype analysis, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide cell proliferation assay, and cell sensitivity to chemotherapeutic drugs. In a complex study of 42 patients with syringomyelobulbia with the aid of EMG and EEG the author most frequently observed symptoms of damage of the descending root and the nuclei of the 5th nerve, the nuclei of the 9, 10 and 12 nerves, as well as nystagmus and the Horner symptom.

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Anaphylatoxin binding and degradation by rat peritoneal mast cells. Glucocorticoids can reverse hemodynamic disturbances and dependence on catecholamines in septic shock. These findings provide convincing evidence that wild-type mice expressing PARP1 cannot compensate for the loss of PARP1 in tumor cells and strengthen the importance of the role of PARP1 as a transcriptional coactivator of HIF-1-dependent gene expression during tumor progression. In this work, we evaluate the impact of these issues by comparing the growth and properties of human-virus and within-human PPI networks with and without structural models. The authors describe two new cases of NS with acute lymphoblastic leukemia (ALL), which were part of a series of 370 consecutive ALL untreated patients. They were divided into two groups on the basis of the absence or coexistence of abnormal serum lipid pattern. Native gel electrophoresis of human telomerase distinguishes active complexes with or without dyskerin. These elaborate mechanisms are required for neuronal development and maintenance of the nervous system. Vitrectomy was performed for vitreous hemorrhage (five patients), macular pucker (two patients), macular hole (one patient), and zyrtec generic drowsy rhegmatogenous retinal detachment (one patient).

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Deletions in epidermal keratins leading to alterations in filament organization in vivo and in intermediate filament assembly in vitro. The calculations for maximal doses and volumes of OAR suggest that the risk of secondary cancer induction after IORT is lower than compared to APBI and EBRT. U report as a community feedback mechanism registered a low response rate. Social skills and classroom behavior among adolescents with mild mental retardation. The effect of thromboxane B2 (TxB2) on inactivation of prostaglandin E2 (PGE2) by the rat isolated perfused lung has been studied. Motor evacuatory function of the gastrointestinal tract after extensive resection of the small intestine in dogs. Thus, in choosing a regression model, a researcher should give strong consideration to how well the model reflects (presumed) intrinsic properties of the phenomena under study, even if the consideration leads to the choice of a nonlinear model. Allele-specific oligonucleotides are covalently immobilized on glass slides in arrays of 3 mm spots.

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