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Bactramin (Trimethoprim)
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Bactramin

Bactramin is a combination of two synthetic (man-made) antibiotics, sulfamethoxazole and trimethoprim. Both drugs reduce the ability of some bacteria to utilize folic acid for growing. Sulfamethoxazole is an anti-bacterial sulfonamide, a sulfa drug.

Other names for this medication:
Assepium, Bacsul, Bactramin, Bactricid, Baktar, Baktimol, Bakton, Bascul, Berlocid, Bioprim, Canibioprim, Ciplin, Dhatrin, Eliprim, Gantrisin, Kaftrim, Megatrim, Meprim, Methoxasol, Metrim, Netocur, Nopil, Novidrine, Nufaprim, Octrim, Pehatrim, Primazol, Purbac, Qiftrim, Regtin, Resprim, Servitrim, Sulphax, Tabrol, Triforam, Trimethox, Trimol, Tritenk, Zaxol

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Also known as: Trimethoprim

Description

Sulfamethoxazole and trimethoprim combination is used to treat infections including urinary tract infections, middle ear infections (otitis media), bronchitis, traveler's diarrhea, and shigellosis (bacillary dysentery). This medicine is also used to prevent or treat Pneumocystis jiroveci pneumonia or Pneumocystis carinii pneumonia (PCP), a very serious kind of pneumonia. This type of pneumonia occurs more commonly in patients whose immune systems are not working normally, including cancer patients, transplant patients, and patients with acquired immune deficiency syndrome (AIDS).

Sulfamethoxazole and trimethoprim combination is an antibiotic. It works by eliminating the bacteria that cause many kinds of infections. This medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.

Dosage

Adults: The usual adult dosage in the treatment of urinary tract infections is 1 Bactramin DS (double strength) tablet or 2 Bactramin tablets every 12 hours for 10 to 14 days. An identical daily dosage is used for 5 days in the treatment of shigellosis.

Children: The recommended dose for children with urinary tract infections or acute otitis media is 40 mg/kg sulfamethoxazole and 8 mg/kg trimethoprim per 24 hours, given in two divided doses every 12 hours for 10 days. An identical daily dosage is used for 5 days in the treatment of shigellosis.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include loss of appetite, vomiting, fever, blood in your urine, yellowing of your skin or eyes, confusion, or loss of consciousness.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Side effects

The most common side effects associated with Bactramin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Before taking sulfamethoxazole with trimethoprim, tell your doctor or pharmacist if you are allergic to sulfa medications or trimethoprim; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, certain blood disorders (such as porphyria, anemia due to folate vitamin deficiency), history of blood disorders caused by trimethoprim or sulfa medications, vitamin deficiency (folate or folic acid), severe allergies, asthma, decreased bone marrow function (bone marrow suppression), a certain metabolic disorder (G6PD deficiency), underactive thyroid, mineral imbalances (such as high level of potassium or low level of sodium in the blood). Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths or sunlamps. Use a sunscreen and wear protective clothing when outdoors. If you have diabetes, this product may affect your blood sugar levels. Check your blood sugar levels regularly as directed by your doctor. Tell your doctor immediately if you have symptoms of low blood sugar (see Side Effects section). Your doctor may need to adjust your diabetes medication, exercise program, or diet. Older adults may be more sensitive to the side effects of this drug, especially skin reactions, blood disorders, easy bleeding/bruising, and a high potassium blood level. Patients with AIDS may be more sensitive to the side effects of this drug, especially skin reactions, fever, and blood disorders. This medication is not recommended for use during pregnancy especially near the expected delivery date because of possible harm to the unborn baby. Consult your doctor for more details. This drug passes into breast milk. While there have been no reports of harm to healthy infants, this drug may have undesirable effects on infants who are ill or premature or have certain disorders (jaundice, high blood levels of bilirubin, G6PD deficiency). Therefore, breast-feeding is not recommended for infants with these conditions. Consult your doctor before breast-feeding.

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Structure of the repeating unit of the intracellular polysaccharide from Mycobacterium convolutum 240. The effects of fasting, diabetes, and hypophysectomy on rat adipose pyruvate kinase. Most infected individuals do not experience symptoms requiring treatment, and roughly half of those treated will become free of detectable virus for an extended, perhaps permanent, period. To estimate the association between local clean indoor air ordinances and prenatal maternal smoking across 351 municipalities in Massachusetts before the 2004 statewide ban and to test the effect of time since ordinance adoption on the association. In addition, the solid compactum of the late secretory phase was marked by the development of very late antigen-1 in the predecidual cells. Cytoplasmic delivery of liposome-entrapped antigen from an endocytic compartment allows the exogenous antigen to gain access to the class I presentation pathway.

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This DNA polymorphism has 10 alleles and a heterozygosity of 0.82 and can be easily typed using the polymerase chain reaction. Most injuries are overuse types related to excessive pitch counts, premature use of breaking pitches, and improper pitching mechanics. Heterogeneity of murine adherent interleukin-2-activated killer cells. Malignancy, associated malformations and aneuploidy are observed infrequently. The insulin receptor is expressed in two different isoforms (HIR-A and HIR-B). By contrast, at pH 7.5 the two-chain form is not phosphorylated at all. We accessed prospectively collected OHS and OKS data for patients undergoing lower limb joint arthroplasty at a single orthopaedic teaching hospital during a five-year period. Effect of insulin-induced hypoglycemia, 2-deoxyglucose-induced glucose cytopenia, and hyperglycemia on cardiovascular tone in normal and diabetic rats. In summary, both direct-image data and spatial-transform data are found to be important. GSCs maintained under adherent serum cultured conditions continued to proliferate and initiate tumor formation with efficiencies similar to GSCs maintained under proliferating (neurosphere) conditions.

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The guidelines issued by the German Federal Chamber of Physicians on quality assurance in x-ray diagnostics and CT result in a considerable reduction of patient doses. It can be concluded that angiogenesis may act as a predictor of prognosis of endometrioid adenocarcinoma. This article reviews the controversies surrounding the treatment of hyponatremia with special emphasis on risk to benefit ratio of different therapeutic strategies. At Embryonic Day 14 (E14), the highest signal for 5-HT1C was found in the choroid plexus, while the marginal/intermediate (m/i) zones of the midbrain, brain stem (including monoaminergic groups), and spinal cord also displayed label. Health-related quality of life before, 1 month after, and 9 months after intensive care in medical cardiovascular and pulmonary patients. Molecular phylogenetics of Australo-Papuan possums and gliders (family Petauridae). As recommended by international standards the cornea should be maintained in a specific temperature range (2 degrees -8 degrees C) to guarantee its viability.

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